Mr Zelaya told Venezuelan television on Thursday that he was getting ready to return to his country from neighbouring Nicaragua.
"I am preparing various alternatives: by air, by land, and others," he told Venezuelan television.
The foreign minister in the deposed government, Patricia Rodas, said Mr Zelaya was returning to wage a "final battle" against those who ousted him.
On Friday, thousands of Zelaya supporters blocked key Honduran roads for a second day, in preparation for his possible return.
Nicaraguan President Daniel Ortega said the interim government had deployed forces on the border with his country.
"I don't know why they are so terrorised by President Zelaya that they have put tanks and cannons, artillery, mortars, anti-aircraft guns to shoot President Zelaya down if he tries to enter by plane," he said.
Interim Honduran President Roberto Micheletti took over at the head of a military-backed government after Mr Zelaya was bundled out of the country on 28 June.
Mr Zelaya was forced out amid a dispute with the country's Congress and the courts over his plans to hold a non-binding public consultation to ask people whether they supported moves to change the constitution.
Mr Zelaya's critics said the move was aimed at removing the current one-term limit on serving as president, so paving the way for his possible re-election.